Arts at CERN announces the winners of the Collide awards

Particle detectors meet canvas

CERN experiment sees hints of a rare kaon decay

Beams are back in the LHC

“Humpty Dumpty” particle discovered

A new era of precision for antimatter research

First LHC test collisions of 2018

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Sunday, May 27, 2018

AbstractUp-regulation of glucose transport drives keratinocyte proliferation, whereas its inhibition offers therapeutic potential against psoriasis.Copyright © 2018, American Association for the Advancement of Science Contributors Riekelt HoutkooperLaboratory Genetic Metabolic Diseases, Academic Medical Center, Amsterdam, 1105 AZ Amsterdam, Netherlands. Email: r.h.houtkooper{at}amc.nl
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Modeling remodelingPatients with valvular heart disease such as aortic stenosis (narrowing of the aortic valve in the heart) receive artificial or bioprosthetic valve replacements, but these have limited longevity and cannot grow with younger patients. Emmert et al. used computational modeling to design tissue-engineered heart valves from polymer scaffolds


Stem cell transplants in pigs with spinal cord injuryNeural precursor cells (NPCs) hold promise for treating spinal cord injury (SCI). Testing viability and engraftment properties of NPC transplants in large-animal models is necessary for understanding the clinical potential of this approach. In a new study, Strnadel et al. transplanted


Humidity—Harbinger of health?Low environmental humidity can aggravate symptoms of atopic dermatitis (AD), an inflammatory skin disease. Seltmann et al. investigated the link between humidity and epidermal barrier function. Using a mouse model that exhibits AD-like symptoms, they found that high humidity reduced epidermal thickness and skin inflammation. Chloride channel


RSV gives innate immunity the runaroundAsthma can be exacerbated by pathogens such as respiratory syncytial virus (RSV); prostaglandin D2 (PGD2) is also important in asthma and is being investigated as a therapeutic target. Werder et al. used multiple models to examine how RSV infection may perturb immune responses and


AbstractExposure to peripheral inflammation induces microglia to alter subsequent course of stroke and Alzheimer’s pathologies.Copyright © 2018, American Association for the Advancement of Science Contributors Frank J. AttenelloDepartment of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. Email: attenell{at}usc.edu
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AbstractAcellular heart valve grafts optimized through computational modeling recellularize and function in sheep for up to 1 year (Emmert et al., this issue).Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Workshttp://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an article


Predicting progression in a T cell lymphomaMycosis fungoides (MF) is an often indolent cutaneous T cell lymphoma identifiable by the T cell receptor gene TCRB in skin biopsies. de Masson et al. performed high-throughput sequencing of MF skin lesions to determine whether the frequency of the most abundant TCRB


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